Article
Mutations in genes encoding extracellular matrix proteins suppress the emb-5 gastrulation defect in Caenorhabditis elegans.
Molecular & general genetics : MGG - 1 Jul 1998
Nishiwaki K, Miwa J
Abstract excerpt
The second division of the gut precursor E cells is lethally accelerated during Caenorhabditis elegans gastrulation by mutations in the emb-5 gene, which encodes a presumed nuclear protein. We have isolated suppressor mutations of the temperature-sensitive allele emb-5(hc61), screened for them am...
Topics
- Alleles
- Animals
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Cell Division
- Collagen
- Embryo, Nonmammalian
- Extracellular Matrix Proteins
- Gastrula
- Gene Expression Regulation, Developmental
- Genes
- Genes, Suppressor
- Genotype
- Glucagon
- Glucagon-Like Peptide 1
- Helminth Proteins
- Molecular Chaperones
- Mutation