Embryonic lethality caused by mutations in basement membrane collagen of C. elegans.

doi:10.1038/349707a0

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Article

Embryonic lethality caused by mutations in basement membrane collagen of C. elegans.

Nature - 21 Feb 1991

Guo X D, Johnson J J, Kramer J M

Abstract excerpt

Basement membranes are specialized forms of extracellular matrix with important functions in development. A major structural component of basement membranes is type IV collagen, a heterotrimer of two alpha 1(IV) and one alpha 2(IV) chains, which forms a complex, polygonal network associated with...

Topics

Amino Acid Sequence
Animals
Base Sequence
Basement Membrane
Caenorhabditis
Collagen
Humans
Molecular Sequence Data
Mutation
Sequence Homology, Nucleic Acid
Temperature

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