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Article

The Drosophila embargoed gene is required for larval progression and encodes the functional homolog of schizosaccharomyces Crm1.

Genetics - 1 Aug 2000

Collier S, Chan H Y, Toda T, McKimmie C, Johnson G, Adler P N, O'Kane C, Ashburner M

Abstract excerpt

The CRM1 (Exportin 1) protein is a receptor for leucine-rich nuclear export signal sequences. We have molecularly characterized the Drosophila melanogaster embargoed (emb) gene and find that it encodes a product with 49 and 71% sequence identity to the fission yeast Schizosaccharomyces pombe and human CRM1 proteins, respectively. We show that expression of the emb cDNA is sufficient to suppress the growth...

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Identifiers

PMID: 10924475
DOI: 10.1093/genetics/155.4.1799
PMCID: PMC1461193

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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