Article
Modified and Mutant Porins in the Study on Molecular Basis of Non- Specific Diffusion.
Current protein & peptide science - 1 Jan 2017
Novikova Olga D, Portnyagina Olga Yu, Solov'eva Tamara F
Abstract excerpt
Site-directed mutagenesis allows elucidation of the basic principles of the porin-driven membrane permeability and opens the possibility for the modulation of functional states of porin channels. The review is aimed to show the advantages of using mutant and chemically modified porins for obtaining detailed information about molecular mechanisms that underlie the non-specific transmembrane diffusion. We...
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