Angiotensin I-converting enzyme (ACE): estimation of DNA haplotypes in unrelated individuals using denaturing gradient gel blots.

doi:10.1007/BF00202855

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Article

Angiotensin I-converting enzyme (ACE): estimation of DNA haplotypes in unrelated individuals using denaturing gradient gel blots.

Human genetics - 1 Aug 1994

Doria A, Warram J H, Rich S S, Krolewski A S

Abstract excerpt

The angiotensin I-converting enzyme (ACE) gene (17q23) is a candidate gene for essential hypertension and related diseases, but investigation of its role in human pathology is hampered by a lack of identified polymorphisms. Currently, a 287-bp insertion/deletion (I/D) RFLP in intron 16 represents...

Topics

Alleles
Base Sequence
Blotting, Southern
DNA
DNA Probes
Electrophoresis, Polyacrylamide Gel
Genetic Linkage
Haplotypes
Humans
Molecular Sequence Data
Nucleic Acid Denaturation
Nucleic Acid Hybridization
Peptidyl-Dipeptidase A
Polymorphism, Genetic

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PMID: 8045557
DOI: 10.1007/BF00202855

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8045557-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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