Article
p53 Expression as a Diagnostic Biomarker in Ulcerative Colitis-Associated Cancer.
International journal of molecular sciences - 16 Jun 2017
Kobayashi Kazuhiro, Tomita Hiroyuki, Shimizu Masahito, Tanaka Takuji, Suzui Natsuko, Miyazaki Tatsuhiko, Hara Akira
Abstract excerpt
Ulcerative colitis (UC) is defined as an idiopathic inflammatory disorder primarily involving the mucosa and submucosa of the colon. UC-associated colon cancers (also known as colitic cancers) develop through the inflammation-dysplasia sequence, which is a major problem affecting the prognosis of patients with UC. It is therefore very important to detect malignancy from UC at an early stage. As precancerous...
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