Article
Factors influencing recombination frequency and distribution in a human meiotic crossover hotspot.
Human molecular genetics - 1 Aug 2005
Jeffreys Alec J, Neumann Rita
Abstract excerpt
Little is known about the factors that influence the frequency and distribution of meiotic recombination events within human crossover hotspots. We now describe the detailed analysis of sperm recombination in the NID1 hotspot. Like the neighbouring MS32 hotspot, the NID1 hotspot is associated with a minisatellite, suggesting that hotspots predispose DNA to tandem repetition. Unlike MS32, crossover resolution...
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