Article
The histone H3 acetylase dGcn5 is a key player in Drosophila melanogaster metamorphosis.
Molecular and cellular biology - 1 Sept 2005
Carré Clément, Szymczak Dimitri, Pidoux Josette, Antoniewski Christophe
Abstract excerpt
Although it has been well established that histone acetyltransferases (HATs) are involved in the modulation of chromatin structure and gene transcription, there is only little information on their developmental role in higher organisms. Gcn5 was the first transcription factor with HAT activity identified in eukaryotes. Here we report the isolation and characterization of Drosophila melanogaster dGcn5 mutants....
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