Missense translation errors in Saccharomyces cerevisiae.

doi:10.1006/jmbi.1998.1976

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Article

Missense translation errors in Saccharomyces cerevisiae.

Journal of molecular biology - 11 Sept 1998

Stansfield I, Jones K M, Herbert P, Lewendon A, Shaw W V, Tuite M F

Abstract excerpt

We describe the development of a novel plasmid-based assay for measuring the in vivo frequency of misincorporation of amino acids into polypeptide chains in the yeast Saccharomyces cerevisiae. The assay is based upon the measurement of the catalytic activity of an active site mutant of type III c...

Topics

Alanine
Binding Sites
Chloramphenicol O-Acetyltransferase
Codon
Cycloheximide
Genetic Techniques
Histidine
Mutation
Paromomycin
Protein Biosynthesis
Ribosomal Protein S9
Ribosomal Proteins
Saccharomyces cerevisiae
Tyrosine

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