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Article

ACE insertion/deletion genotype affects bradykinin metabolism.

Journal of cardiovascular pharmacology - 1 Sept 1998

Brown N J, Blais C, Gandhi S K, Adam A

Abstract excerpt

A deletion allele of the angiotensin-converting enzyme (ACE) gene has been associated with increased serum ACE activity, enhanced conversion of angiotensin (Ang) I to Ang II, and cardiovascular morbidity. This study tested the hypothesis that the ACE deletion allele is also associated with enhanced degradation of bradykinin, a vasoprotective peptide. Metabolism of synthetic bradykinin was measured in sera...

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PMID: 9733349
DOI: 10.1097/00005344-199809000-00006

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ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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ACE insertion/deletion genotype affects bradykinin metabolism.PMID 9733349Read ↗

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Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction.Semantic proximity Read ↗

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