ACE insertion/deletion genotype affects bradykinin metabolism.

doi:10.1097/00005344-199809000-00006

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Article

ACE insertion/deletion genotype affects bradykinin metabolism.

Journal of cardiovascular pharmacology - 1 Sept 1998

Brown N J, Blais C, Gandhi S K, Adam A

Abstract excerpt

A deletion allele of the angiotensin-converting enzyme (ACE) gene has been associated with increased serum ACE activity, enhanced conversion of angiotensin (Ang) I to Ang II, and cardiovascular morbidity. This study tested the hypothesis that the ACE deletion allele is also associated with enhanc...

Topics

Adult
Bradykinin
Female
Genotype
Half-Life
Humans
Male
Peptidyl-Dipeptidase A

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