Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional consequences of angiotensin-converting enzyme gene polymorphism on N-acetyl-Ser-Asp-Lys-Pro degradation and angiotensin II production.

Journal of molecular medicine (Berlin, Germany) - 1 Aug 2002

Azizi Michel, Junot Christophe, Ezan Eric, Hallouin Marie-Charlotte, Guyene Tam, Ménard Joël

Abstract excerpt

Studies analyzing the biochemical and hemodynamic consequences of the insertion/deletion (I/D) polymorphism of the angiotensin I converting enzyme gene on angiotensin I and bradykinin metabolism have provided divergent results. Twelve DD and 12 II normotensive subjects were infused for 15 min with angiotensin I (30 ng kg(-1) x min(-1)) and with another angiotensin I converting enzyme substrate not related to the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiotensin-Converting Enzyme Inhibitors
Share to Cross-Over Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Homozygote

Share to Oligopeptides

Share to Peptidyl-Dipeptidase A

Share to Polymorphism, Genetic

Share to Single-Blind Method

Share to Substrate Specificity

Source

Identifiers

PMID: 12185449
DOI: 10.1007/s00109-002-0357-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional consequences of angiotensin-converting enzyme gene polymorphism on N-acetyl-Ser-Asp-Lys-Pro degradation and angiotensin II production.PMID 12185449Read ↗

ACE insertion/deletion genotype affects bradykinin metabolism.Semantic proximity Read ↗

Angiotensin-converting enzyme insertion/deletion polymorphism modulates the human in vivo metabolism of bradykinin.Semantic proximity Read ↗

Enhanced pressor response to angiotensin I in normotensive men with the deletion genotype (DD) for angiotensin-converting enzyme.Semantic proximity Read ↗

The angiotensin-converting enzyme gene polymorphism and responses to angiotensins and bradykinin in the human forearm.Semantic proximity Read ↗

Pressor and hormonal responses to angiotensin I infusion in healthy subjects of different angiotensin-converting enzyme genotypes.Semantic proximity Read ↗

Different contributions of the angiotensin-converting enzyme C-domain and N-domain in subjects with the angiotensin-converting enzyme II and DD genotype.Semantic proximity Read ↗

Genetics of angiotensin I-converting enzyme.Semantic proximity Read ↗

Deletion/insertion polymorphism in the angiotension-converting enzyme gene as a risk factor in the Slovenian patients with coronary heart disease.Semantic proximity Read ↗

Neutral endopeptidase and angiotensin I converting enzyme insertion/deletion gene polymorphism in humans.Semantic proximity Read ↗

Effect of angiotensin-converting enzyme insertion/deletion genotype on collagen type I synthesis and degradation in patients with atrial fibrillation and arterial hypertension.Semantic proximity Read ↗

Polymorphism insertion/deletion of the ACE gene and ambulatory blood pressure circadian variability in essential hypertension.Semantic proximity Read ↗

Involvement of renin-angiotensin system in pressure-flow relationship: role of angiotensin-converting enzyme gene polymorphism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.