ACE (I/D) genotype as a predictor of the magnitude and duration of the response to an ACE inhibitor drug (enalaprilat) in humans.

doi:10.1161/01.cir.98.20.2148

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Article

ACE (I/D) genotype as a predictor of the magnitude and duration of the response to an ACE inhibitor drug (enalaprilat) in humans.

Circulation - 17 Nov 1998

Ueda S, Meredith P A, Morton J J, Connell J M, Elliott H L

Abstract excerpt

BACKGROUND: We have investigated the possible effects of contrasting ACE (I/D) genotypes on the responses to the ACE inhibitor enalaprilat in normotensive men. METHODS AND RESULTS: Subjects with DD (n=12) and II (n=11) ACE genotypes received an intravenous infusion of enalaprilat or placebo. Pres...

Topics

Adult
Angiotensin II
Angiotensin-Converting Enzyme Inhibitors
Blood Pressure
Enalaprilat
Genotype
Humans
Male
Peptidyl-Dipeptidase A
Renin-Angiotensin System
Time Factors

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