Article
Endothelial cell damage and angiotensin-converting enzyme insertion/deletion genotype in elderly hypertensive patients.
Journal of the American College of Cardiology - 1 Aug 1998
Kario K, Matsuo T, Kobayashi H, Kanai N, Hoshide S, Mitsuhashi T, Ikeda U, Nishiuma S, Matsuo M, Shimada K
Abstract excerpt
OBJECTIVES: The purpose of this study was to investigate the angiotensin-converting enzyme (ACE) insertion/deletion (I/D) genotype and endothelial cell dysfunction or hypercoagulable state in elderly hypertensive patients. BACKGROUND: Angiotensin-converting enzyme (ACE) insertion/ deletion (I/D) polymorphism was recently reported to be associated with various cardiovascular diseases. However, the precise...
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