Abnormal eye development associated with Cat4a, a dominant mouse cataract mutation on chromosome 8.

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Article

Abnormal eye development associated with Cat4a, a dominant mouse cataract mutation on chromosome 8.

Investigative ophthalmology & visual science - 1 Sept 1998

Grimes P A, Koeberlein B, Favor J, Neuhäuser-Klaus A, Stambolian D

Abstract excerpt

PURPOSE: Cat4a, one of four mutant alleles at the mouse Cat4 locus, causes central corneal opacity and anterior polar cataract in heterozygotes and microphthalmia in homozygotes. The Cat4 locus has been mapped to chromosome 8, 31 cM from the centromere. In this study ocular development of Cat4a m...

Topics

Abnormalities, Multiple
Animals
Anterior Eye Segment
Cataract
Chromosome Mapping
Chromosomes
Eye
Eye Abnormalities
Female
Lens, Crystalline
Mice
Mice, Inbred C3H
Mice, Mutant Strains
Morphogenesis
Mutation
Pregnancy

Source

Open in PubMed

Identifiers

PMID: 9727409

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9727409-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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