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Article

Abnormal eye development associated with Cat4a, a dominant mouse cataract mutation on chromosome 8.

Investigative ophthalmology & visual science - 1 Sept 1998

Grimes P A, Koeberlein B, Favor J, Neuhäuser-Klaus A, Stambolian D

Abstract excerpt

PURPOSE: Cat4a, one of four mutant alleles at the mouse Cat4 locus, causes central corneal opacity and anterior polar cataract in heterozygotes and microphthalmia in homozygotes. The Cat4 locus has been mapped to chromosome 8, 31 cM from the centromere. In this study ocular development of Cat4a mutant mice was investigated to characterize the defects in eye morphogenesis. METHODS: Serial sections from eyes of...

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PMID: 9727409

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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