Article
AP-2alpha transcription factor is required for early morphogenesis of the lens vesicle.
Developmental biology - 1 Feb 1999
West-Mays J A, Zhang J, Nottoli T, Hagopian-Donaldson S, Libby D, Strissel K J, Williams T
Abstract excerpt
AP-2 transcription factors are a family of retinoic acid-responsive genes, which are involved in complex morphogenetic processes. In the current study, we determine the requirement for AP-2alpha in early morphogenesis of the eye by examining the nature of the ocular defects in AP-2alpha null and...
Topics
- Animals
- Animals, Newborn
- Aquaporins
- Chimera
- DNA-Binding Proteins
- Eye
- Eye Proteins
- Gene Expression Regulation, Developmental
- Histocytochemistry
- Homeodomain Proteins
- Immunohistochemistry
- Lens, Crystalline
- Membrane Glycoproteins
- Mice
- Mice, Knockout
- Morphogenesis
- PAX6 Transcription Factor
- Paired Box Transcription Factors