Multigenic and imprinting control of ovarian granulosa cell tumorigenesis in mice.

Article

Multigenic and imprinting control of ovarian granulosa cell tumorigenesis in mice.

Cancer research - 15 Aug 1998

Beamer W G, Shultz K L, Tennent B J, Nadeau J H, Churchill G A, Eicher E M

Abstract excerpt

Spontaneous juvenile ovarian granulosa cell (GC) tumors that occur in young girls are similar to GC carcinomas that develop in SWR-derived inbred mice. We analyzed female offspring from a series of matings among SWR and SJL inbred mice for chromosomal loci underlying tumor susceptibility. Intercr...

Topics

Alleles
Animals
Crosses, Genetic
Disease Susceptibility
Female
Genetic Markers
Genotype
Granulosa Cell Tumor
Logistic Models
Mice
Ovarian Neoplasms
Species Specificity

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.