Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chromosome X loci and spontaneous granulosa cell tumor development in SWR mice: epigenetics and epistasis at work for an ovarian phenotype.

Epigenetics - 1 Feb 2013

Dorward Ann M, Yaskowiak Edward S, Smith Kerri N, Stanford Kaitlyn R, Shultz Kathryn L, Beamer Wesley G

Abstract excerpt

Females of the SWR/Bm (SWR) inbred mouse strain possess a unique susceptibility to juvenile-onset tumors originating from the granulosa cells (GC) of the ovarian follicles. Tumor susceptibility is an inherited, polygenic trait in SWR females, minimally involving an oncogenic Granulosa cell tumor susceptibility (Gct) locus on chromosome (Chr) 4 (Gct1), and two GC tumor susceptibility modifier genes mapped to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epistasis, Genetic
Share to Granulosa Cell Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Inbred Strains

Share to Ovarian Neoplasms

Share to Penetrance

Share to Receptors, Androgen

Share to X Chromosome

Source

Open in PubMed Open full text

Identifiers

PMID: 23299801
DOI: 10.4161/epi.23399
PMCID: PMC3592904

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chromosome X loci and spontaneous granulosa cell tumor development in SWR mice: epigenetics and epistasis at work for an ovarian phenotype.PMID 23299801Read ↗

High-resolution genetic map of X-linked juvenile-type granulosa cell tumor susceptibility genes in mouse.Semantic proximity Read ↗

Distal Chr 4 harbors a genetic locus (Gct1) fundamental for spontaneous ovarian granulosa cell tumorigenesis in a mouse model.Semantic proximity Read ↗

Fine map of the Gct1 spontaneous ovarian granulosa cell tumor locus.Semantic proximity Read ↗

Multigenic and imprinting control of ovarian granulosa cell tumorigenesis in mice.Semantic proximity Read ↗

Genetic susceptibility for C19 androgen induction of ovarian granulosa cell tumorigenesis in SWXJ strains of mice.Semantic proximity Read ↗

Genetics of Ovarian Differentiation: <i>Rspo1</i>, a Major PlayerSemantic proximity Read ↗

Granulosa cell tumorigenesis in genetically hypogonadal-immunodeficient mice grafted with ovaries from tumor-susceptible donors.Semantic proximity Read ↗

Testicular germ cell tumor susceptibility genes from the consomic 129.MOLF-Chr19 mouse strain.Semantic proximity Read ↗

129/Sv mice--a model system for studying germ cell biology and testicular cancer.Semantic proximity Read ↗

HS6ST1 Insufficiency Causes Self-Limited Delayed Puberty in Contrast With Other GnRH Deficiency Genes.Semantic proximity Read ↗

Enhancers and suppressors of testicular cancer susceptibility in single- and double-mutant mice.Semantic proximity Read ↗

Testicular germ cell tumors in mice: new ways to study a genetically complex trait.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.