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Article

Fine map of the Gct1 spontaneous ovarian granulosa cell tumor locus.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Feb 2013

Smith Kerri N, Halfyard Sarah J, Yaskowiak Edward S, Shultz Kathryn L, Beamer Wesley G, Dorward Ann M

Abstract excerpt

The spontaneous development of juvenile-onset, ovarian granulosa cell (GC) tumors in the SWR/Bm (SWR) inbred mouse strain is a model for juvenile-type GC tumors that appear in infants and young girls. GC tumor susceptibility is supported by multiple Granulosa cell tumor (Gct) loci, but the Gct1 locus on Chr 4 derived from SWR strain background is fundamental for GC tumor development and uniquely responsive to the...

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Identifiers

PMID: 23179634
DOI: 10.1007/s00335-012-9439-6
PMCID: PMC3560948

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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