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Article

Identification of distinct molecular phenotypes in cultured gastrointestinal smooth muscle cells.

Gastroenterology - 1 Sept 1998

Brittingham J, Phiel C, Trzyna W C, Gabbeta V, McHugh K M

Abstract excerpt

BACKGROUND & AIMS: Cultured gastrointestinal smooth muscle cells have been shown to dedifferentiate and reinitiate their myogenic program in vitro. The aim of this study was to determine whether the cellular phenotypes observed in vitro were similar to those previously characterized in vivo. METHODS: Differential isoactin expression was examined in primary cultures of intestinal smooth muscle cells (ISMCs) by...

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PMID: 9721158
DOI: 10.1016/s0016-5085(98)70140-4

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