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Article

Characterization of the 3' untranslated region of mouse DNA topoisomerase IIalpha mRNA.

Gene - 30 Jul 1998

Kobayashi M, Adachi N, Koyama H

Abstract excerpt

Expression of DNA topoisomerase IIalpha protein varies through the cell cycle with its peak in G2/M. This cell-cycle-dependent expression depends on changes in topoisomerase IIalpha mRNA stability as well as promoter activity. We isolated the 3' genomic region of the mouse topoisomerase IIalpha gene and investigated whether or not the 3' untranslated region (UTR) of the topoisomerase IIalpha mRNA participates in...

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PMID: 9714832
DOI: 10.1016/s0378-1119(98)00283-2

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