Article
Characterization of the 3' untranslated region of mouse DNA topoisomerase IIalpha mRNA.
Gene - 30 Jul 1998
Kobayashi M, Adachi N, Koyama H
Abstract excerpt
Expression of DNA topoisomerase IIalpha protein varies through the cell cycle with its peak in G2/M. This cell-cycle-dependent expression depends on changes in topoisomerase IIalpha mRNA stability as well as promoter activity. We isolated the 3' genomic region of the mouse topoisomerase IIalpha g...
Topics
- 3T3 Cells
- Alternative Splicing
- Amino Acid Sequence
- Animals
- Antigens, Neoplasm
- Base Sequence
- CHO Cells
- Cloning, Molecular
- Conserved Sequence
- Cricetinae
- Cricetulus
- DNA Topoisomerases, Type II
- DNA-Binding Proteins
- Gene Expression Regulation, Enzymologic
- Genetic Variation
- HeLa Cells
- Humans
- Isoenzymes