Expression of the laminin-A chain is down-regulated by a non-canonical polyadenylation signal.

doi:10.1111/j.1432-1033.1993.tb18144.x

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Article

Expression of the laminin-A chain is down-regulated by a non-canonical polyadenylation signal.

European journal of biochemistry - 15 Aug 1993

Gottschling C, Huber J, Oberbäumer I

Abstract excerpt

It is well accepted that 3' untranslated regions (UTR) are an essential part of mRNA. However, little is known in detail about the contribution of different regions of 3' UTR on synthesis, stability and translatability of their mRNA. In addition to the highly conserved hexanucleotide AAUAAA, some...

Topics

Base Sequence
Cloning, Molecular
DNA
Down-Regulation
Escherichia coli
Gene Expression
Laminin
Molecular Sequence Data
Mutagenesis, Site-Directed
Mutation
Oligonucleotides
Poly A
Protein Biosynthesis
RNA, Messenger

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