Article
New insights into donor directionality of mating-type switching in Schizosaccharomyces pombe.
PLoS genetics - 1 May 2018
Maki Takahisa, Ogura Naoto, Haber James E, Iwasaki Hiroshi, Thon Geneviève
Abstract excerpt
Mating-type switching in Schizosaccharomyces pombe entails programmed gene conversion events regulated by DNA replication, heterochromatin, and the HP1-like chromodomain protein Swi6. The whole mechanism remains to be fully understood. Using a gene deletion library, we screened ~ 3400 mutants for defects in the donor selection step where a heterochromatic locus, mat2-P or mat3-M, is chosen to convert the...
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