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Article

Chromodomain protein Swi6-mediated role of DNA polymerase alpha in establishment of silencing in fission Yeast.

The Journal of biological chemistry - 21 Dec 2001

Ahmed S, Saini S, Arora S, Singh J

Abstract excerpt

Although DNA replication has been thought to play an important role in the silencing of mating type loci in Saccharomyces cerevisiae, recent studies indicate that silencing can be decoupled from replication. In Schizosaccharomyces pombe, mating type silencing is brought about by the trans-acting proteins, namely Swi6, Clr1-Clr4, and Rhp6, in cooperation with the cis-acting silencers. The latter contain an...

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PMID: 11581276
DOI: 10.1074/jbc.M109186200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Chromodomain protein Swi6-mediated role of DNA polymerase alpha in establishment of silencing in fission Yeast.PMID 11581276Read ↗

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Establishment and maintenance of a heterochromatin domain.Semantic proximity Read ↗

A novel type of silencing factor, Clr2, is necessary for transcriptional silencing at various chromosomal locations in the fission yeast Schizosaccharomyces pombe.Semantic proximity Read ↗

The chromodomain protein Swi6: a key component at fission yeast centromeres.Semantic proximity Read ↗

Identification of Uhp1, a ubiquitinated histone-like protein, as a target/mediator of Rhp6 in mating-type silencing in fission yeast.Semantic proximity Read ↗

Regulation of Swi6/HP1-dependent heterochromatin assembly by cooperation of components of the mitogen-activated protein kinase pathway and a histone deacetylase Clr6.Semantic proximity Read ↗

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PCNA connects DNA replication to epigenetic inheritance in yeast.Semantic proximity Read ↗

DNA polymerase α (swi7) and the flap endonuclease Fen1 (rad2) act together in the S-phase alkylation damage response in S. pombe.Semantic proximity Read ↗

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