Article
Angiotensin I converting enzyme gene polymorphisms in systemic lupus erythematosus: decreased prevalence of DD genotype in African American patients.
Clinical nephrology - 1 Jul 1998
Tassiulas I O, Aksentijevich I, Salmon J E, Kim Y, Yarboro C H, Vaughan E M, Davis J C, Scott D L, Austin H A, Klippel J H, Balow J E, Gourley M F, Boumpas D T
Abstract excerpt
The presence of the D (deletion) allele at the angiotensin converting enzyme (ACE) gene has been associated with a) adverse vascular events contributing to early mortality and b) progressive deterioration of renal function in a variety of chronic glomerular diseases. We investigated the potential...
Topics
- Adult
- Alleles
- Analysis of Variance
- Black People
- Chi-Square Distribution
- Female
- Gene Deletion
- Genotype
- Humans
- Lupus Erythematosus, Systemic
- Male
- Peptidyl-Dipeptidase A
- Polymorphism, Genetic
- Prevalence