Article
Association between the angiotensin-converting enzyme insertion/deletion polymorphism and susceptibility to systemic lupus erythematosus: a meta-analysis.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Sept 2013
Lee Young Ho, Choi Sung Jae, Ji Jong Dae, Song Gwan Gyu
Abstract excerpt
OBJECTIVE: The aim of this study was to determine whether the insertion (I) /deletion (D) polymorphism within intron 16 of angiotensin-converting enzyme (ACE) confers susceptibility to systemic lupus erythematosus (SLE) and lupus nephritis (LN). METHODS: A meta-analysis was conducted on the associations between the ACE I/D polymorphism and SLE and LN. RESULTS: A total of 1907 patients with SLE and 1842 controls...
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