Article
Angiotensin-converting enzyme gene polymorphism in patients with systemic lupus.
Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti - 1 Jan 2001
Prkacin I, Novak B, Sertić J, Mrzljak A
Abstract excerpt
The renin-angiotensin-aldosterone system (RAAS) has been considered one of the probable pathophysiologic mechanisms involved in disease progression. Genetic polymorphism of the RAAS has been associated with the clinical course of renal disease. One of the genetic polymorphisms is a deletion or insertion of a 287 base pair fragment in intron 16 of the angiotensin-converting enzyme (ACE) gene. It is known that ACE...
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