Article
Angiotensin-converting enzyme gene polymorphism and risk of sarcoidosis.
American journal of respiratory and critical care medicine - 1 Nov 1998
Maliarik M J, Rybicki B A, Malvitz E, Sheffer R G, Major M, Popovich J, Iannuzzi M C
Abstract excerpt
The angiotensin-converting enzyme (ACE) has been implicated in the pathophysiology of sarcoidosis. Serum ACE levels in normal and sarcoidosis patients are influenced by an insertion (I)/deletion (D) polymorphism in the ACE gene. To elucidate the role of this ACE gene polymorphism in sarcoidosis, we conducted a case-control study in African Americans and Caucasians. The ACE gene (I/D) polymorphism did not differ...
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