Article
Angiotensin-converting enzyme (insertion/deletion) and endothelial nitric oxide synthase polymorphisms in patients with systemic lupus erythematosus.
The Journal of rheumatology - 1 Sept 2004
Douglas Glenn, Reilly Christopher, Dooley Mary Anne, Page Grier, Cooper Glinda, Gilkeson Gary
Abstract excerpt
OBJECTIVE: Genetic polymorphisms in the angiotensin-converting enzyme (ACE) and endothelial nitric oxide synthase (eNOS) are linked with expression and/or progression of renal disease. We hypothesized that polymorphisms in the genes coding for ACE and eNOS may influence the development and/or progression of systemic lupus erythematosus (SLE) and lupus nephritis given their linkage with other renal diseases....
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