Article
Association of angiotensin-converting enzyme (ACE) I/D variation with biochemical parameters and oxidative stress markers in systemic lupus erythematosus patients in west of Iran.
Molecular biology reports - 1 Oct 2023
Kiani Amir, Elieh-Ali-Komi Daniel, Bahrehmand Fariborz, Mostafaei Shayan, Vaisi-Raygani Asad, Baniamerian Hosein, Aghaz Farank, Tanhapour Maryam, Shakiba Ebrahim, Rahimi Zohreh, Pourmotabbed Tayebeh
Abstract excerpt
PURPOSE: We aimed to study insertion/deletion (I/D) variation (rs4646994) of ACE gene in a group of SLE patients in west of Iran and its possible relationship with oxidative stress. METHOD AND RESULTS: Genotypes and allele frequencies related to ACE (I/D) variation were determined in 108 SLE patients and 110 gender and age-matched healthy controls using PCR. Neopterin, malondialdehyde (MDA), and serum lipid...
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