Article
The MEN1 gene and associated diseases: an update.
Endocrine pathology - 1 Jan 2001
Tsukada T, Yamaguchi K, Kameya T
Abstract excerpt
Heterozygous germline mutations of the tumor suppressor gene MEN1 are responsible for multiple endocrine neoplasia type 1 (MEN1), a dominantly inherited familial cancer syndrome characterized by the combined occurrence of pituitary, parathyroid, and enteropancreatic tumors. Various types of mutations likely causing loss of the gene function have been identified throughout the entire gene region in patients with...
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