Article
Association between apolipoprotein E epsilon4 and the rate of cognitive decline in community-dwelling elderly individuals with and without dementia.
Archives of neurology - 1 Aug 1998
Jonker C, Schmand B, Lindeboom J, Havekes L M, Launer L J
Abstract excerpt
OBJECTIVE: To determine whether the apolipoprotein E epsilon4 allele (apoE epsilon4) is associated with cognitive decline in individuals with and without dementia, we conducted a 4-year longitudinal study of subjects with a range of cognitive function. SETTING: At baseline, respondents (n=511) we...
Topics
- Aged
- Aged, 80 and over
- Alleles
- Apolipoproteins E
- Cognition
- Dementia
- Female
- Humans
- Longitudinal Studies
- Male
- Neuropsychological Tests
- Phenotype
- Residence Characteristics
- Severity of Illness Index