Article
Apolipoprotein E status as a predictor of the development of Alzheimer's disease in memory-impaired individuals.
JAMA - 26 Apr 1995
Petersen R C, Smith G E, Ivnik R J, Tangalos E G, Schaid D J, Thibodeau S N, Kokmen E, Waring S C, Kurland L T
Abstract excerpt
OBJECTIVE: The outcome of patients with mild cognitive impairment is not known, yet these patients present a difficult dilemma for the clinician. This study was designed to characterize the outcome of a group of patients with mild cognitive impairment and to determine whether the presence of the...
Topics
- Aged
- Alleles
- Alzheimer Disease
- Apolipoproteins E
- Base Sequence
- Cognition Disorders
- Disease Progression
- Female
- Gene Frequency
- Genotype
- Humans
- Longitudinal Studies
