Article
Immunoglobulin double isotype-producing hybridomas isolated from an autoimmune (NZB x NZW)F1 mouse.
Hybridoma - 1 Jun 1998
Payelle-Brogard B, Ragimbeau J, Avrameas S, Christodoulou C
Abstract excerpt
In the sera of (NZB x NZW)F1 (B/W) mice that develop a lupus-like syndrome, increased levels of IgG antibodies (Ab) reacting with TNP have been detected before the appearance of IgG anti-DNA Ab and clinical symptoms. A single injection of trinitrophenyl-bovine serum albumin (TNP/BSA) in physiological saline into a young B/W mouse (3 months old), followed by fusion of its splenocytes 3 days later, gave rise to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.