Immunoglobulin double isotype-producing hybridomas isolated from an autoimmune (NZB x NZW)F1 mouse.

doi:10.1089/hyb.1998.17.289

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Article

Immunoglobulin double isotype-producing hybridomas isolated from an autoimmune (NZB x NZW)F1 mouse.

Hybridoma - 1 Jun 1998

Payelle-Brogard B, Ragimbeau J, Avrameas S, Christodoulou C

Abstract excerpt

In the sera of (NZB x NZW)F1 (B/W) mice that develop a lupus-like syndrome, increased levels of IgG antibodies (Ab) reacting with TNP have been detected before the appearance of IgG anti-DNA Ab and clinical symptoms. A single injection of trinitrophenyl-bovine serum albumin (TNP/BSA) in physiolog...

Topics

Alleles
Amino Acid Sequence
Animals
Antibody Specificity
Autoantibodies
Base Sequence
Enzyme-Linked Immunosorbent Assay
Immunoglobulin Class Switching
Immunoglobulin G
Immunoglobulin Isotypes
Immunoglobulin M
Mice
Molecular Sequence Data

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