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Article

Variable region sequences of pathogenic anti-mouse red blood cell autoantibodies from autoimmune NZB mice.

European journal of immunology - 1 Apr 1990

Reininger L, Shibata T, Ozaki S, Shirai T, Jaton J C, Izui S

Abstract excerpt

New Zealand Black (NZB) mice spontaneously develop a severe autoimmune hemolytic anemia due to the production of anti-mouse red blood cell (MRBC) autoantibodies. The contribution of variable region genes and somatic mutations in the pathogenicity of anti-MRBC autoantibodies was investigated by mRNA sequencing of eight NZB anti-MRBC monoclonal autoantibodies, among which five are capable of inducing anemia in...

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Identifiers

PMID: 2347362
DOI: 10.1002/eji.1830200410

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Variable region sequences of pathogenic anti-mouse red blood cell autoantibodies from autoimmune NZB mice.PMID 2347362Read ↗

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