Article
Unequal fidelity of leading strand and lagging strand DNA replication on the Escherichia coli chromosome.
Proceedings of the National Academy of Sciences of the United States of America - 18 Aug 1998
Fijalkowska I J, Jonczyk P, Tkaczyk M M, Bialoskorska M, Schaaper R M
Abstract excerpt
We have investigated the question whether during chromosomal DNA replication in Escherichia coli the two DNA strands may be replicated with differential accuracy. This possibility of differential replication fidelity arises from the distinct modes of replication in the two strands, one strand (th...
Topics
- Alleles
- Chromosomes, Bacterial
- DNA Repair
- DNA Replication
- DNA, Bacterial
- Drug Resistance, Microbial
- Escherichia coli
- Evolution, Molecular
- Genes, Bacterial
- Lac Operon
- Point Mutation
- Rifampin