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Article

Nature of the SOS-inducing signal in Escherichia coli. The involvement of DNA replication.

Journal of molecular biology - 5 Mar 1990

Sassanfar M, Roberts J W

Abstract excerpt

The SOS genes of Escherichia coli, which include many DNA repair genes, are induced by DNA damage. Although the central biochemical event in induction, activation of RecA protein through binding of single-stranded DNA and ATP to promote cleavage of the LexA repressor, is known, the cellular event that provides this activation following DNA damage has not been well understood. We provide evidence here that the...

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Identifiers

PMID: 2108251
DOI: 10.1016/0022-2836(90)90306-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Nature of the SOS-inducing signal in Escherichia coli. The involvement of DNA replication.PMID 2108251Read ↗

A brief consideration of the SOS inducing signal.Semantic proximity Read ↗

The SOS system.Semantic proximity Read ↗

Mathematical model of the SOS response regulation of an excision repair deficient mutant of Escherichia coli after ultraviolet light irradiation.Semantic proximity Read ↗

Chronology in lesion tolerance gives priority to genetic variability.Semantic proximity Read ↗

Regulation of the SOS response in Bacillus subtilis: evidence for a LexA repressor homolog.Semantic proximity Read ↗

RecJ nuclease is required for SOS induction after introduction of a double-strand break in a RecA loading deficient recB mutant of Escherichia coli.Semantic proximity Read ↗

Novel mechanism for UV sensitivity and apparent UV nonmutability of recA432 mutants: persistent LexA cleavage following SOS induction.Semantic proximity Read ↗

Constitutive and UV-mediated activation of RecA protein: combined effects of recA441 and recF143 mutations and of addition of nucleosides and adenine.Semantic proximity Read ↗

SOS mutator activity: unequal mutagenesis on leading and lagging strands.Semantic proximity Read ↗

Genetic evidence for the requirement of RecA loading activity in SOS induction after UV irradiation in Escherichia coli.Semantic proximity Read ↗

Roles of ExoI and SbcCD nucleases in "reckless" DNA degradation in recA mutants of Escherichia coli.Semantic proximity Read ↗

Requirement of RecBC enzyme and an elevated level of activated RecA for induced stable DNA replication in Escherichia coli.Semantic proximity Read ↗

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