Nature of the SOS-inducing signal in Escherichia coli. The involvement of DNA replication.

doi:10.1016/0022-2836(90)90306-7

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Article

Nature of the SOS-inducing signal in Escherichia coli. The involvement of DNA replication.

Journal of molecular biology - 5 Mar 1990

Sassanfar M, Roberts J W

Abstract excerpt

The SOS genes of Escherichia coli, which include many DNA repair genes, are induced by DNA damage. Although the central biochemical event in induction, activation of RecA protein through binding of single-stranded DNA and ATP to promote cleavage of the LexA repressor, is known, the cellular event...

Topics

Bacterial Proteins
DNA Damage
DNA Repair
DNA Replication
DNA, Bacterial
Escherichia coli
Mitomycin
Mitomycins
Mutation
Rec A Recombinases
Repressor Proteins
SOS Response, Genetics
Serine Endopeptidases
Ultraviolet Rays

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