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Article

Fine-mapping quantitative trait loci affecting murine external ear tissue regeneration in the LG/J by SM/J advanced intercross line.

Heredity - 1 May 2014

Cheverud J M, Lawson H A, Bouckaert K, Kossenkov A V, Showe L C, Cort L, Blankenhorn E P, Bedelbaeva K, Gourevitch D, Zhang Y, Heber-Katz E

Abstract excerpt

External ear hole closure in LG/J mice represents a model of regenerative response. It is accompanied by the formation of a blastema-like structure and the re-growth of multiple tissues, including cartilage. The ability to regenerate tissue is heritable. An F34 advanced intercross line of mice (Wustl:LG,SM-G34) was generated to identify genomic loci involved in ear hole closure over a 30-day healing period. We...

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Identifiers

PMID: 24569637
DOI: 10.1038/hdy.2013.133
PMCID: PMC3998788

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