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Article

Generation of a high-resolution genetic map and a YAC contig of the Lurcher locus on mouse chromosome 6.

Genome research - 1 Nov 1995

Zuo J, De Jager P L, Norman D J, Heintz N

Abstract excerpt

Lurcher (Lc) is a semidominant mouse mutant that displays progressive neurodegeneration during perinatal development. This genetic lesion results in apoptotic neuronal death in a dosage dependent and cell autonomous manner in specific neurons during their terminal differentiation. To understand the molecular basis of the Lc mutation, we have adopted a positional cloning approach based on its location on mouse...

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Identifiers

PMID: 8750197
DOI: 10.1101/gr.5.4.381

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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