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Article

Association of different tumor necrosis factor alpha promoter allele frequencies with ankylosing spondylitis in HLA-B27 positive individuals.

Arthritis and rheumatism - 1 Aug 1998

Höhler T, Schäper T, Schneider P M, Meyer zum Büschenfelde K H, Märker-Hermann E

Abstract excerpt

OBJECTIVE: To investigate the potential association of tumor necrosis factor alpha (TNFalpha) promoter alleles with ankylosing spondylitis. METHODS: DNA from 141 HLA-B27 positive Caucasian patients with ankylosing spondylitis and 46 B27-positive and 99 B27-negative healthy Caucasian controls was investigated by polymerase chain reaction amplification of the TNFalpha promoter region and subsequent dot-blot...

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PMID: 9704649
DOI: 10.1002/1529-0131(199808)41:8<1489::AID-ART20>3.0.CO;2-5

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of different tumor necrosis factor alpha promoter allele frequencies with ankylosing spondylitis in HLA-B27 positive individuals.PMID 9704649Read ↗

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Tumor necrosis factor gene polymorphisms in ankylosing spondylitis.Semantic proximity Read ↗

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The -308.1 polymorphism in the promoter region of the tumor necrosis factor gene is associated with ankylosing spondylitis independent of HLA-B27.Semantic proximity Read ↗

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Low T cell production of TNFalpha and IFNgamma in ankylosing spondylitis: its relation to HLA-B27 and influence of the TNF-308 gene polymorphism.Semantic proximity Read ↗

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