Association of different tumor necrosis factor alpha promoter allele frequencies with ankylosing spondylitis in HLA-B27 positive individuals.

doi:10.1002/1529-0131(199808)41:8<1489::AID-ART20>3.0.CO;2-5

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Association of different tumor necrosis factor alpha promoter allele frequencies with ankylosing spondylitis in HLA-B27 positive individuals.

Arthritis and rheumatism - 1 Aug 1998

Höhler T, Schäper T, Schneider P M, Meyer zum Büschenfelde K H, Märker-Hermann E

Abstract excerpt

OBJECTIVE: To investigate the potential association of tumor necrosis factor alpha (TNFalpha) promoter alleles with ankylosing spondylitis. METHODS: DNA from 141 HLA-B27 positive Caucasian patients with ankylosing spondylitis and 46 B27-positive and 99 B27-negative healthy Caucasian controls was...

Topics

Adolescent
Adult
Age of Onset
Aged
Aged, 80 and over
Alleles
Female
Gene Frequency
Genetic Variation
HLA-B27 Antigen
Humans
Male
Middle Aged
Promoter Regions, Genetic
Spondylitis, Ankylosing
Tumor Necrosis Factor-alpha

Source

Open in PubMed

Identifiers

PMID: 9704649
DOI: 10.1002/1529-0131(199808)41:8<1489::AID-ART20>3.0.CO;2-5

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9704649-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics