Article
Polymorphisms of tumor necrosis factor-α promoter region for susceptibility to HLA-B27-positive ankylosing spondylitis in Korean population.
Rheumatology international - 1 Sept 2011
Chung Won-Tae, Choe Jung-Yoon, Jang Won Cheoul, Park Su Min, Ahn Young Chang, Yoon Il Kyu, Kim Tae-Hwan, Nam Youn-Hyoung, Park Sung-Hoon, Lee Sung-Won, Kim Seong-Kyu
Abstract excerpt
This study designed to assess the relationship between tumor necrosis factor (TNF)-α promoter polymorphisms and disease susceptibility to human leukocyte antigen (HLA)-B27-positive ankylosing spondylitis (AS). One hundred and nineteen HLA-B27(+) AS patients, 95 HLA-B27(+) healthy controls, and 135 random healthy controls were enrolled in this study. Six single nucleotide polymorphisms (SNPs) of the TNF-α promoter...
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