Chromosome fragility and predisposition to childhood malignancies.

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Article

Chromosome fragility and predisposition to childhood malignancies.

Anticancer research - 1 Jan 2000

Kolialexi A, Mavrou A, Tsenghi C, Tsangaris G T, Dafermou E, Tzortzatou F, Polychronopoulou S, Haidas S, Metaxotou C

Abstract excerpt

In order to clarify the possible connection between autosomal folate sensitive Fragile Sites (FS) and genetic susceptibility to haemopoetic disease in children we investigated the frequency and distribution of FS in the Peripheral Blood Lymphocytes (PBL) of 56 children with newly diagnosed and un...

Topics

Adult
Child
Child, Preschool
Chromosome Fragile Sites
Chromosome Fragility
Chromosome Mapping
Female
Genetic Predisposition to Disease
Genomic Imprinting
Humans
Incidence
Infant

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Karyotyping

Leukemia

Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Leukemia, Myeloid, Acute

Lymphocytes

Lymphoma

Source

Open in PubMed

Identifiers

PMID: 9703879

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9703879-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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