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Chromosome fragility and predisposition to childhood malignancies.

Anticancer research - 1 Jan 2000

Kolialexi A, Mavrou A, Tsenghi C, Tsangaris G T, Dafermou E, Tzortzatou F, Polychronopoulou S, Haidas S, Metaxotou C

Abstract excerpt

In order to clarify the possible connection between autosomal folate sensitive Fragile Sites (FS) and genetic susceptibility to haemopoetic disease in children we investigated the frequency and distribution of FS in the Peripheral Blood Lymphocytes (PBL) of 56 children with newly diagnosed and untreated haematologic malignancies and their parents. The incidence was compared with that of 146 normal controls...

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PMID: 9703879

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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