Article
Genetic mechanism of leukemia predisposition in a family with 7 cases of acute myeloid leukemia.
Cancer genetics and cytogenetics - 1 Aug 1994
He L Z, Lu L H, Chen Z Z
Abstract excerpt
This paper describes a family in which seven members, involving three consecutive generations, suffered from acute myeloid leukemia during the past 16 years. The genetic abnormalities were vertically transmitted in a Mendelian dominant manner without sex linkage. Cytogenetic approaches, such as G-banding karyotypes, micronuclei (MN), chromosome aberrations (CA), fragile sites (Fra), cell cycle time (Tc), sister...
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