Article
Alterations of RET oncogene in human adrenal tumors.
Japanese journal of cancer research : Gann - 1 Jun 1998
Lin S R, Yang Y C, Tsai J H, Hsu C H
Abstract excerpt
Previous studies have revealed specific activations of the RET oncogene in multiple endocrine neoplasia type 2 (MEN 2) and thyroid tumors. To understand the role of the RET proto-oncogene activation in sporadic adrenal tumors, we analyzed the alterations of the RET proto-oncogene in the cysteine-rich extracellular domain (exons 6 and 10), the terminal region of the extracellular domain and transmembrane domain...
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