Article
A study of the association between schizophrenia and the dopamine D3 receptor gene.
Human genetics - 1 Oct 1993
Nanko S, Sasaki T, Fukuda R, Hattori M, Dai X Y, Kazamatsuri H, Kuwata S, Juji T, Gill M
Abstract excerpt
A study of the genetic association between schizophrenia and a BalI polymorphism in exon 1 of the dopamine D3 (DRD3) gene, a candidate gene for schizophrenia, was conducted. The polymorphism was examined in 91 patients whose symptoms satisfied DSM-III-R for schizophrenia and 90 controls. There we...
Topics
- Adult
- Alleles
- DNA
- Electrophoresis, Polyacrylamide Gel
- Exons
- Female
- Gene Frequency
- Genotype
- Humans
- Male
- Middle Aged
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Receptors, Dopamine
- Receptors, Dopamine D2
- Receptors, Dopamine D3
- Schizophrenia
