Article
Dopamine D3 receptor gene polymorphism and the psychiatric symptoms seen in first-break schizophrenic patients.
Psychiatric genetics - 1 Jan 1995
Inada T, Sugita T, Dobashi I, Inagaki A, Kitao Y, Matsuda G, Kato S, Takano T, Yagi G, Asai M
Abstract excerpt
To investigate the possible effect of polymorphism at the BalI site of the dopamine D3 receptor gene (DRD3) on the phenotype in human subjects, allele and genotype frequencies for this polymorphic site were examined in 113 schizophrenic patients, including six subgroups, and 48 normal controls. T...
Topics
- Adult
- Aged
- Aged, 80 and over
- Base Sequence
- DNA Primers
- Delusions
- Deoxyribonucleases, Type II Site-Specific
- Female
- Gene Frequency
- Genotype
- Hallucinations
- Homozygote
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Phenotype
- Polymerase Chain Reaction