Article
Relationship between homozygosity at the dopamine D3 receptor gene and schizophrenia.
American journal of medical genetics - 15 Mar 1994
Mant R, Williams J, Asherson P, Parfitt E, McGuffin P, Owen M J
Abstract excerpt
We have reported an association between schizophrenia and homozygosity of a Bal I polymorphism in the first exon of the dopamine D3 receptor gene (Crocq et al.: Journal of Medical Genetics 29:858-860, 1992). The present study consists of an attempt to replicate this finding in a further sample of...
Topics
- Adult
- Alleles
- Antipsychotic Agents
- Base Sequence
- Case-Control Studies
- Chi-Square Distribution
- DNA Primers
- Deoxyribonucleases, Type II Site-Specific
- Female
- Gene Frequency
- Homozygote
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Odds Ratio
- Polymorphism, Restriction Fragment Length
- Receptors, Dopamine
