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CYP2A13, ADH1B, and ADH1C gene polymorphisms and pancreatic cancer risk.

Pancreas - 1 Mar 2010

Mohelnikova-Duchonova Beatrice, Vrana David, Holcatova Ivana, Ryska Miroslav, Smerhovsky Zdenek, Soucek Pavel

Abstract excerpt

OBJECTIVES: Pancreatic carcinoma etiology and molecular pathogenesis are weakly understood. Based on the assumption that genetic variation in carcinogen metabolism further modifies the risk of exposure-related cancers, we studied the association of polymorphisms in the tobacco carcinogen-metabolizing gene CYP2A13 (Arg101Stop) and the alcohol-metabolizing genes ADH1B (Arg48His) and ADH1C (Ile350Val) with...

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PMID: 19812523
DOI: 10.1097/MPA.0b013e3181bab6c2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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