Article
GST, NAT1, CYP1A1 polymorphisms and risk of esophageal and gastric adenocarcinomas.
Cancer detection and prevention - 1 Jan 2007
Wideroff Louise, Vaughan Thomas L, Farin Federico M, Gammon Marilie D, Risch Harvey, Stanford Janet L, Chow Wong-Ho
Abstract excerpt
BACKGROUND: Polymorphisms in glutathione-S-transferase (GST), N-acetyltransferase (NAT) 1, and CYP1A1 genes have been suggested as susceptibility factors for esophageal and gastric adenocarcinomas, but have not been consistently linked to elevated risks. In a population-based case-control study, we examined risks in relation to polymorphisms of the following genes: GSTP1; GSTM1; GSTT1; NAT1; and CYP1A1. METHODS:...
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