Article
Increased levels of NAD(P)H: quinone oxidoreductase 1 (NQO1) in pancreatic tissues from smokers and pancreatic adenocarcinomas: A potential biomarker of early damage in the pancreas.
Cell biology and toxicology - 1 Mar 2006
Lyn-Cook B D, Yan-Sanders Y, Moore S, Taylor S, Word B, Hammons G J
Abstract excerpt
NAD(P)H:quinone oxidoreductase 1 (NQO1) is elevated in several human tumors. This study was conducted to determine whether increased levels of NQO1 expression also occur in human pancreatic tumor tissue, and to compare expression levels in nontumorous tissue from smokers with those in nonsmokers....
Topics
- Adenocarcinoma
- Adult
- Aged
- Aged, 80 and over
- Base Sequence
- Biomarkers, Tumor
- Case-Control Studies
- Female
- Genetic Predisposition to Disease
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- NAD(P)H Dehydrogenase (Quinone)
- Pancreas