Article
Association between N-acetyltransferase 2 polymorphisms and pancreatic cancer risk: a meta-analysis.
Genetics and molecular research : GMR - 17 Dec 2015
Liang J X, Gao W, Liang Y, Zhou X M
Abstract excerpt
N-acetyltransferase 2 (NAT2) is an essential phase II enzyme in the metabolism of aromatic and heterocyclic amines and of hydrazines. NAT2 activity can be divided into three phenotypes: rapid, intermediate, and slow. Studies identifying an association between NAT2 polymorphism and the risk of pancreatic cancer have shown conflicting results. In order to assess this relationship comprehensively, we performed a...
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